Boost protein yields & quality through fine-tuning of gene expression by increasing genetic diversity
VALIDOGEN's Pichia pastoris experts will closely work with you on your project to optimize production of your protein choosing the proper tools to provide the most favorable conditions matching your requirements.
Building on Pichia´s inherent potential, VALIDOGEN established UNLOCK PICHIA - an exclusive yield-enhancing protein production toolbox, standing out due to its diversity of expression tools and expression strategies. A proprietary AOX1 promoter library and a diverse set of platform strains provide the genetic diversity necessary for fine-tuning of protein expression. Notably, 2nd generation promoter variants from VALIDOGEN's exclusive promoter library offer more flexibility by providing methanol-free protein production processes. Timely adjusted co-expression of helper proteins allows for maximization of protein production. VALIDOGEN's unique high-throughput microscale screening and cultivation expertise and protocols ensure fast and reliable identification of the best performing genetic arrangement out of thousands of Pichia strains producing the target protein at different levels.