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Tailor-made glycoproteins from Pichia pastoris

Enhanced glycoprotein production - UNLOCK PICHIA boosting Pichia Glycoswitch®
VALIDOGEN's powerful yield enhancing Pichia pastoris expression platform UNLOCK PICHIA and Pichia GlycoSwitch® - a unique expression system for the production of glycoproteins with human-like glycosylation patterns - are available as a unique package from VALIDOGEN. This unique combination of technologies acting synergistically leads to a high performance platform for the production of recombinant glycoproteins with superior product yields and uniform Man5- or other human-like glycoforms.

GlycoSwitch® strains from VALIDOGEN incorporate proprietary promoters and chaperones that significantly enhance protein yields.

Key benefits

  • Homogeneous, uniform glycoproteins 
  • Unrivalled production levels through VALIDOGEN's yield enhancing Pichia pastoris expression platform UNLOCK PICHIA
  • Production of tailor-made glycoproteins
  • Elimination of high-mannose glycosylation

 

 

Further elements of UNLOCK PICHIA - VALIDOGEN's Pichia pastoris protein production toolbox

UNLOCK PICHIA - discover the broadest Pichia pastoris protein production toolbox

Unparalleled spectrum of exclusive expression tools and ingenious expression strategies
01

MeOH-inducible and MeOH-free AOX1 promoter libraries

Maximize productivity by fine-tuning of protein expression
Details
02

Diverse platform strains

Meet your needs for various applications
Details
03

Proprietary helper factors

Enhancement of product yield and quality – timely adjusted for maximum output
Details
04

High-throughput combinatorial screening

Rapid and reliable generation & identification of high-level production strains matching protein quantity and quality attributes
Details
05

Glycoengineering tools

Enhanced glycoprotein production – UNLOCK PICHIA combined with Pichia GlycoSwitch®
Details
06

Half-life extension

Albumin fusion proteins - biopharmaceuticals with increased half-life
Details
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News

VALIDOGEN to present at PICHIA 2021, online conference, March 24 - April 1

Pichia 2021, online conference "Don't miss latest insights into UNLOCK ...
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New case study on VHH antibody expression underlines the power of UNLOCK PICHIA

We conducted a series of case studies, demonstrating the yield-enhancing ...
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Downloads

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