Pichia pastoris Protein Expression Excellence
UNLOCK PICHIA® - Advanced Pichia strain and process development
We are a leading contract research & development organization specializing in recombinant protein expression using our exclusive UNLOCK PICHIA® protein expression technology. Our Pichia pastoris (also known as Komagataella phaffii) experts have been serving the protein production industry for more than 15 years.
With our UNLOCK PICHIA® platform we apply a broad portfolio of technologies for successful and economically viable expression of your protein in Pichia.
We offer lean expression feasibility studies including delivery of purified lab-scale protein samples, generate high-performance Pichia pastoris production strains in competitive time frames, develop scalable bioreactor cultivation protocols, and undertake protein purification process optimization. Services are complemented with technology transfer for smooth implementation at your facility or with your CMO.
UNLOCK PICHIA®
Our expertise is paired with our exclusive UNLOCK PICHIA® technology toolbox, which consists of proprietary methanol-inducible and methanol-free promoters, platform strains, novel secretion signals, and expression-enhancing helper factors.
This toolbox allows for both methanol-induced and methanol-free expression systems, in addition to platform strains without the requirement for antimicrobial resistance genes (ARMs-free). Time-controlled target protein expression and co-expression of helper proteins allow for maximization of protein yields.
VALIDOGEN’s predictive high-throughput screening abilities and expertly developed protocols ensure fast and reliable identification of the best-performing genetic arrangement selected from thousands of Pichia strains assessed in parallel.
We are a leading contract research & development organization specializing in recombinant protein expression using our exclusive UNLOCK PICHIA® protein expression technology. Our Pichia pastoris (also known as Komagataella phaffii) experts have been serving the protein production industry for more than 15 years.
With our UNLOCK PICHIA® platform we apply a broad portfolio of technologies for successful and economically viable expression of your protein in Pichia.
We offer lean expression feasibility studies including delivery of purified lab-scale protein samples, generate high-performance Pichia pastoris production strains in competitive time frames, develop scalable bioreactor cultivation protocols, and undertake protein purification process optimization. Services are complemented with technology transfer for smooth implementation at your facility or with your CMO.
UNLOCK PICHIA®
Our expertise is paired with our exclusive UNLOCK PICHIA® technology toolbox, which consists of proprietary methanol-inducible and methanol-free promoters, platform strains, novel secretion signals, and expression-enhancing helper factors.
This toolbox allows for both methanol-induced and methanol-free expression systems, in addition to platform strains without the requirement for antimicrobial resistance genes (ARMs-free). Time-controlled target protein expression and co-expression of helper proteins allow for maximization of protein yields.
VALIDOGEN’s predictive high-throughput screening abilities and expertly developed protocols ensure fast and reliable identification of the best-performing genetic arrangement selected from thousands of Pichia strains assessed in parallel.
Working with VALIDOGEN
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VALIDOGEN's expert team is happy to discuss your project requirements. Send any project related requests to project@validogen.com, directly to our scientists, or use our contact form.