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UNLOCK PICHIA - PRODUCTIVITY THROUGH DIVERSITY

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Today's Feature: 
VTU's bioprocess development program for maximization of productivity
 

Robust, scalable, well characterized – maximize productivity of your bioprocess without compromising product quality 
 
You need stable, robust and scalable processes for commercial manufacturing? 

Are you looking for a process yielding consistent product quality?

Are you seeking to acquire process knowledge?


Pichia processes at VTU show extraordinarily high space-time yields and typical product concentrations of 10 - 20 g/l at raw product purities of 80 - 90 % in culture supernatant before downstream processing.

VTU Technology offers straightforward bioprocess development and optimization services. This capability is essential for the elucidation of key process parameters (considering potential scale-up constraints) and for achieving process productivity, quality and robustness levels that will support commercial production of recombinant proteins. 

Protein production processes developed in VTU's labs have been shown to be robust and scalable.

To date, several VTU customers have licensed and successfully scaled-up VTU's Pichia processes for the manufacture of recombinant proteins to volumes ranging from several hundred to more than 10,000 l.

Comprehensive documentation and professional support guarantee sound technology transfer of the optimized fermentation process to your production site and straightforward implementation in large-scale production facilities.

Key benefits
  • Boosted space time yields through optimized VTU cultivation protocols
  • Reduced manufacturing costs
  • Scalable, robust, transferable and cmc-ready manufacturing system
  • Short time lines and high flexibility
 
Technology
  • Established platform processes and extensive know-how and experience serve as a basis for successful optimization
  • State of the art bioreactors equipped with comprehensive online analytics
  • Design of experiment software tools for efficient parameter scouting and full DoE process development
VTU Technology highlighting its Pichia toolbox at BIO International Convention, June 4 - 7, 2018, Boston, US

Thomas Purkarthofer and Roland Weis will be representing VTU Technology and would be pleased to get in touch at the event. Please contact Tom directly or via BIO's partnering system for the arrangement of a meeting.
 

VTU Technology GmbH
Parkring 18, 8074 Raaba-Grambach, Austria
office.technology@vtu.com, +43 (316) 4009 4000
 
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