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UNLOCK PICHIA

VALIDOGEN's broad Pichia pastoris protein production toolbox

PRODUCTIVITY through DIVERSITY

Boost protein yields & quality through fine-tuning of gene expression by increasing genetic diversity

We fine-tune the expression of your protein by generating a large number of different genetic constellations unlocking Pichia´s potential for successful production of fully active, high quality proteins.

VALIDOGEN's Pichia pastoris experts will closely work with you on your project to optimize production of your protein choosing the proper tools to provide the most favorable conditions matching your requirements.

Building on Pichia´s inherent potential, VALIDOGEN established UNLOCK PICHIA - an exclusive yield-enhancing protein production toolbox, standing out due to its diversity of expression tools and expression strategies. A proprietary AOX1 promoter library and a diverse set of platform strains provide the genetic diversity necessary for fine-tuning of protein expression. Notably, 2nd generation promoter variants from VALIDOGEN's exclusive promoter library offer more flexibility by providing methanol-free protein production processes. Timely adjusted co-expression of helper proteins allows for maximization of protein production. VALIDOGEN's unique high-throughput microscale screening and cultivation expertise and protocols ensure fast and reliable identification of the best performing genetic arrangement out of thousands of Pichia strains producing the target protein at different levels.

 

Technology

UNLOCK PICHIA - discover the broadest Pichia pastoris protein production toolbox

Unparalleled spectrum of exclusive expression tools and ingenious expression strategies
01

MeOH-inducible and MeOH-free AOX1 promoter libraries

Maximize productivity by fine-tuning of protein expression
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02

Diverse platform strains

Meet your needs for various applications
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03

Proprietary helper factors

Enhancement of product yield and quality – timely adjusted for maximum output
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04

High-throughput combinatorial screening

Rapid and reliable generation & identification of high-level production strains matching protein quantity and quality attributes
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05

Glycoengineering tools

Enhanced glycoprotein production – UNLOCK PICHIA combined with Pichia GlycoSwitch®
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06

Half-life extension

Albumin fusion proteins - biopharmaceuticals with increased half-life
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News

VTU Technology is now VALIDOGEN

VTU Technology is now VALIDOGEN
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Meet us at  

Conferences & Exhibitions  
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Downloads

Company folder and brochures

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