With manufacturability in mind
Targeted and time-saving generation of high-productivity strains is an integral part of effective bioprocess development. VALIDOGEN is addressing today's protein manufacturing needs by early consideration of production strain and process requirements.
The versatility of its UNLOCK PICHIA protein production platform enables such considerations and provides the tools and genetic diversity necessary for fine-tuning of protein expression. Key to productivity and development speed is the targeted application of the full toolbox by high-throughput generation and comparison of thousands of combinations of different promoter variants, platform strains, helper factors, secretion signals or production regimes.
All aspects of manufacturability from targeted debottlenecking for yield maximization, to product quality (including glycosylation issues) and regulatory requirements (antibiotic-free clone selection) as well as process safety (methanol-free production) and process economy are considered and integrated at the earliest possible stage during strain development. Hence, effective industrial protein production strain generation and production process development is assured paving the way for economically viable manufacturing.
Please contact us if you are interested to learn more about VALIDOGEN's strain development approach or any other service directly by speaking to our team or use the possibility to connect via BIO DIGITAL starting this week.
Dr. Iskandar Dib - iskandar.dib@validogen.com
Dr. Thomas Purkarthofer - thomas.purkarthofer@validogen.com
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VALIDOGEN is part of BIO DIGITAL 2021, June 10-18
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We will be attending BIO Digital taking place on 10-11th and 14-18th June 2021.
Thomas Purkarthofer, Head of Business Development is available for meetings. Feel free to set-up your virtual meeting via the online partnering portal.
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UNLOCK PICHIA advantages
- Broadest Pichia platform: numerous expression tools & different strategies
- Targeted debottlenecking for yield maximization
- Secreted products - beneficial starting point for protein purification
- Complete absence of methanol through VALIDOGEN´s methanol-free promoters
- Tailor-made glycoproteins - UNLOCK PICHIA boosting Pichia GlycoSwitch®
- Stable, robust and scalable processes for commercial manufacturing
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For more information please visit our website or contact us directly:
VALIDOGEN GmbH
Parkring 18, 8074 Raaba-Grambach, Austria
office@validogen.com, T: + 43 316 4009 4000
www.validogen.com
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